Disrupting the immunosuppressive myeloid microenvironment unlocks the next era of cancer immunotherapy
ABOUT
Adaptam Therapeutics is pioneering cancer immunotherapies specifically targeting the immunosuppressive myeloid tumor microenvironment to bring better therapies to oncology patients. Backed by Criteria Bio Ventures, Adaptam is developing antibody-based therapies directed to novel targets, including glycan-binding proteins and Siglecs, which are expressed in immunosuppressive myeloid cells such as tumor-associated macrophages (TAMs). Adaptam, a spin-off from CIC bioGUNE, has received prestigious national and European grants, including funding from the European Research Council (ERC).
BOARD OF DIRECTORS
Asis Palazon, PhD
CEO/CSO & Founder
Asis is the Founder and CEO/CSO of Adaptam Therapeutics, where he leads the development of innovative biotherapeutics in immuno-oncology. Prior to Adaptam, Asis served as an Ikerbasque Research Professor and Principal Investigator of the Cancer Immunology and Immunotherapy laboratory at CIC bioGUNE, focusing on the mechanistic understanding of T cell and myeloid cell biology in the efficacy of immunotherapies. Before that, he held positions at Medimmune/AstraZeneca in Cambridge, UK, contributing to the development of therapeutic antibodies. Asis received his training in cancer immunology at CIMA in Pamplona, Spain and the University of Cambridge, UK. He holds a Ph.D. in Biomedicine, specializing in the interplay between immune cells and the tumor microenvironment.
Pablo Cironi, PhD
Chairman
Pablo joined Criteria Bio Ventures in 2018, where he plays a pivotal role in Criteria Bio Ventures' Investment Team, leveraging his extensive experience as a life science investor. He serves as a board director at AbolerIS Pharma, Minoryx Therapeutics, MedLumics, and Aelix Therapeutics, and has held positions on various portfolio company boards including SANIFIT Therapeutics, Splice Bio, iProteos, GlyCardial Diagnostics, and AptaTargets. Before joining Criteria Bio Ventures, Pablo served as Head of the Technology and Business Development Office at the Centre for Genomic Regulation (CRG) from 2013 to 2018. During his tenure, he spearheaded the CRG’s Innovation and Business Strategy, focusing on strategic planning and implementation. Pablo earned his degree in Chemistry from the University of Buenos Aires, followed by a Ph.D. in Organic Chemistry from the University of Barcelona. He conducted postdoctoral research in Synthetic Biology at Harvard Medical School, where he explored new classes of protein-based therapeutics.
Salvatore Cappadona, PhD
Board Member
Salvatore is a Senior Associate at Criteria Bio Ventures, where he plays a core role in the Investment Team, leveraging his expertise in scouting, analyzing, and building biotech companies. At CBV, he also serves as board director at Adaptam Therapeutics and board observer at MedLumics and Wooptix. Before joining Criteria Bio Ventures, Salvatore was a Business Development Manager at the Centre for Genomic Regulation (CRG) Technology and Business Development Office (TBDO), where he assisted CRG entrepreneurs in assessing business opportunities and structuring their business strategies, leading to successful venture creation. Salvatore holds an MSc in Biomedical Engineering and a PhD in Bioengineering from Politecnico di Milano. His postgraduate credentials include postdoctoral research experience in top-ranking proteomics groups and executive education in science management at IE Business School.
José M Mato, PhD
Board Member
José M Mato, PhD
Board Member
José M is a Board Member at Adaptam Therapeutics. He is the founder and General Director of the Centers CIC bioGUNE in Bilbao and CIC biomaGUNE in San Sebastián, and Research Professor at the Spanish National Research Council (CSIC). José M holds a Ph.D. in Biochemistry from Leiden University, where he was awarded the prestigious CJ Kok prize for his thesis. He completed postdoctoral training at the Biozentrum of the University of Basel and the National Institutes of Health. Throughout his career, José M has held various academic positions, including faculty member at the Jiménez Díaz Foundation in Madrid, Professor at the Faculty of Medicine of the University of Navarra, and Visiting Professor at the University of Pennsylvania and Thomas Jefferson University. From 1992 to 1996, he served as President of the CSIC and was honored with the Spanish National Research Prize in Medicine in 2004.
NEWS
Adaptam Therapeutics raises €3 million to pioneer cancer immunotherapi...
Financing round, led by founding investor Criteria Bio Ventures, will enable Adaptam to advance first-in-class antibody-based therapies, including antibody-drug conjugates (ADCs) and bispecific antibodies, for multiple oncology indications Adaptam intends to disrupt the immunosuppressive tumor microenvironment to deliver more effective therapies for patients...
Adaptam Therapeutics receives an ERC Proof of Concept grant to develop...
The European Research Council (ERC) has awarded an ERC Proof of Concept grant to Prof. Asis Palazon, founder and CEO/CSO of Adaptam Therapeutics. This funding will foster the early stages of development of antibody-based therapies focused on novel targets, including glycan-binding proteins and Siglecs, which are expressed in immunosuppressive myeloid cells such...
Researchers from Adaptam Therapeutics, spin-off from CIC bioGUNE, reve...
Adaptam Therapeutics, a pioneering biotech company focused on developing next-generation immunotherapies, announces the publication of a research paper in Nature Communications. The study sheds light on critical structural details of Siglec-15, a novel immune modulator, providing new opportunities for targeted cancer therapies. San Sebastián, Spain – June 20,...
CONTACT
Adaptam Therapeutics
Gipuzkoa Science and Technology Park
Tandem Building / Paseo Miramón 170
20014 Donostia-San Sebastián – Spain







