Disrupting the immunosuppressive myeloid microenvironment unlocks the next era of cancer immunotherapy

 

ABOUT

Adaptam Therapeutics is pioneering cancer immunotherapies specifically targeting the immunosuppressive myeloid tumor microenvironment to bring better therapies to oncology patients. Backed by Criteria Bio Ventures, Adaptam is developing antibody-based therapies directed to novel targets, including glycan-binding proteins and Siglecs, which are expressed in immunosuppressive myeloid cells such as tumor-associated macrophages (TAMs). Adaptam, a spin-off from CIC bioGUNE, has received prestigious national and European grants, including funding from the European Research Council (ERC).

 

BOARD OF DIRECTORS

Asis Palazon, PhD

CEO/CSO & Founder

Asis Palazon, PhD

CEO/CSO & Founder

Asis is the Founder and CEO/CSO of Adaptam Therapeutics, where he leads the development of innovative biotherapeutics in immuno-oncology. Prior to Adaptam, Asis served as an Ikerbasque Research Professor and Principal Investigator of the Cancer Immunology and Immunotherapy laboratory at CIC bioGUNE, focusing on the mechanistic understanding of T cell and myeloid cell biology in the efficacy of immunotherapies. Before that, he held positions at Medimmune/AstraZeneca in Cambridge, UK, contributing to the development of therapeutic antibodies. Asis received his training in cancer immunology at CIMA in Pamplona, Spain and the University of Cambridge, UK. He holds a Ph.D. in Biomedicine, specializing in the interplay between immune cells and the tumor microenvironment.

Pablo Cironi, PhD

Chairman

Pablo Cironi, PhD

Chairman

Pablo joined Criteria Bio Ventures in 2018, where he plays a pivotal role in Criteria Bio Ventures' Investment Team, leveraging his extensive experience as a life science investor. He serves as a board director at AbolerIS Pharma, Minoryx Therapeutics, MedLumics, and Aelix Therapeutics, and has held positions on various portfolio company boards including SANIFIT Therapeutics, Splice Bio, iProteos, GlyCardial Diagnostics, and AptaTargets. Before joining Criteria Bio Ventures, Pablo served as Head of the Technology and Business Development Office at the Centre for Genomic Regulation (CRG) from 2013 to 2018. During his tenure, he spearheaded the CRG’s Innovation and Business Strategy, focusing on strategic planning and implementation. Pablo earned his degree in Chemistry from the University of Buenos Aires, followed by a Ph.D. in Organic Chemistry from the University of Barcelona. He conducted postdoctoral research in Synthetic Biology at Harvard Medical School, where he explored new classes of protein-based therapeutics.

Ruben Sebastian, PhD

Board Member

Ruben Sebastian, PhD

Board Member

Ruben is a Senior Associate at Criteria Bio Ventures and focuses on building and investing in biotech companies. Ruben is board director at Adaptam Therapeutics, board observer at AbolerIS Pharma, and has been the due diligence lead on Tolerance Bio. Before joining Criteria Bio Ventures, Ruben was a Technology and Business Development fellow at the Centre for Genomic Regulation (CRG) technology transfer office, where he advised entrepreneurs on R&D, intellectual property protection, and commercialization strategies. He also provided due diligence support in biopharma and therapeutics deals as an independent consultant to early-stage investment firms in Spain and the US. Ruben holds a Ph.D. in Biomedicine from the Centre for Genomic Regulation (CRG), where he studied genome organization and epigenetics in stem cells and during cellular reprogramming and contributed to developing novel cell therapies with engineered chemokines for regenerative medicine, and a master’s degree in Cancer Biology from the University of Barcelona.

José M Mato, PhD

Board Member

José M Mato, PhD

Board Member

José M is a Board Member at Adaptam Therapeutics. He is the founder and General Director of the Centers CIC bioGUNE in Bilbao and CIC biomaGUNE in San Sebastián, and Research Professor at the Spanish National Research Council (CSIC). José M holds a Ph.D. in Biochemistry from Leiden University, where he was awarded the prestigious CJ Kok prize for his thesis. He completed postdoctoral training at the Biozentrum of the University of Basel and the National Institutes of Health. Throughout his career, José M has held various academic positions, including faculty member at the Jiménez Díaz Foundation in Madrid, Professor at the Faculty of Medicine of the University of Navarra, and Visiting Professor at the University of Pennsylvania and Thomas Jefferson University. From 1992 to 1996, he served as President of the CSIC and was honored with the Spanish National Research Prize in Medicine in 2004.

INVESTORS

CriteriaBioVenturesVert

PARTNERS & FUNDING AGENCIES

Group 11
Group 17
Group 12
Group 14
Group 15
Group 13
Group 11
Group 12
Group 15
Group 17
Group 14
Group 13
 

NEWS

Adaptam Therapeutics receives an ERC Proof of Concept grant to develop …

The European Research Council (ERC) has awarded an ERC Proof of Concept grant to Prof. Asis Palazon, founder and CEO/CSO of Adaptam Therapeutics. This funding will foster the early stages of development of antibody-based therapies focused on novel targets, including glycan-binding proteins and Siglecs, which are expressed in immunosuppressive myeloid cells such...

read more

Researchers from Adaptam Therapeutics, spin-off from CIC bioGUNE, …

Adaptam Therapeutics, a pioneering biotech company focused on developing next-generation immunotherapies, announces the publication of a research paper in Nature Communications. The study sheds light on critical structural details of Siglec-15, a novel immune modulator, providing new opportunities for targeted cancer therapies. San Sebastián, Spain – June 20,...

read more
 

CONTACT

Adaptam Therapeutics

Gipuzkoa Science and Technology Park
Tandem Building / Paseo Miramón 170
20014 Donostia-San Sebastián – Spain

1 + 2 =